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( A ) Oxygen levels (PO 2 (mmHg)) in cell culture media under control conditions and following exposure to hypoxia for 24 hr in <t>the</t> <t>C-chamber</t> <t>hypoxia</t> <t>sub-chamber</t> (Biospherix; unpaired t -test, p<0.0001); ( B ) Hierarchical clustering, using Ward’s criterion, of the first three principal components of the normalized gene expression profiles of all 17,777 genes passing quality control shows clear separation of 12 and 24 hr hypoxia-exposed samples versus control and from reoxygenated samples. Bar charts: mean ± s.e.m.
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( A ) Oxygen levels (PO 2 (mmHg)) in cell culture media under control conditions and following exposure to hypoxia for 24 hr in <t>the</t> <t>C-chamber</t> <t>hypoxia</t> <t>sub-chamber</t> (Biospherix; unpaired t -test, p<0.0001); ( B ) Hierarchical clustering, using Ward’s criterion, of the first three principal components of the normalized gene expression profiles of all 17,777 genes passing quality control shows clear separation of 12 and 24 hr hypoxia-exposed samples versus control and from reoxygenated samples. Bar charts: mean ± s.e.m.
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( A ) Oxygen levels (PO 2 (mmHg)) in cell culture media under control conditions and following exposure to hypoxia for 24 hr in <t>the</t> <t>C-chamber</t> <t>hypoxia</t> <t>sub-chamber</t> (Biospherix; unpaired t -test, p<0.0001); ( B ) Hierarchical clustering, using Ward’s criterion, of the first three principal components of the normalized gene expression profiles of all 17,777 genes passing quality control shows clear separation of 12 and 24 hr hypoxia-exposed samples versus control and from reoxygenated samples. Bar charts: mean ± s.e.m.
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chamber slides nalge nunc - by Bioz Stars, 2026-08
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dedicated incubator chamber  (BioSpherix)
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( A ) Oxygen levels (PO 2 (mmHg)) in cell culture media under control conditions and following exposure to hypoxia for 24 hr in <t>the</t> <t>C-chamber</t> <t>hypoxia</t> <t>sub-chamber</t> (Biospherix; unpaired t -test, p<0.0001); ( B ) Hierarchical clustering, using Ward’s criterion, of the first three principal components of the normalized gene expression profiles of all 17,777 genes passing quality control shows clear separation of 12 and 24 hr hypoxia-exposed samples versus control and from reoxygenated samples. Bar charts: mean ± s.e.m.
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dedicated incubator chamber - by Bioz Stars, 2026-08
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c-chamber  (BioSpherix)
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( A ) Oxygen levels (PO 2 (mmHg)) in cell culture media under control conditions and following exposure to hypoxia for 24 hr in <t>the</t> <t>C-chamber</t> <t>hypoxia</t> <t>sub-chamber</t> (Biospherix; unpaired t -test, p<0.0001); ( B ) Hierarchical clustering, using Ward’s criterion, of the first three principal components of the normalized gene expression profiles of all 17,777 genes passing quality control shows clear separation of 12 and 24 hr hypoxia-exposed samples versus control and from reoxygenated samples. Bar charts: mean ± s.e.m.
C Chamber, supplied by BioSpherix, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-chamber/custom%40c174%4010%2E1021%2Fcbmi%2E5c00273?v=BioSpherix
Average 96 stars, based on 1 article reviews
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c chambers  (BioSpherix)
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BioSpherix c chambers
( A ) Oxygen levels (PO 2 (mmHg)) in cell culture media under control conditions and following exposure to hypoxia for 24 hr in <t>the</t> <t>C-chamber</t> <t>hypoxia</t> <t>sub-chamber</t> (Biospherix; unpaired t -test, p<0.0001); ( B ) Hierarchical clustering, using Ward’s criterion, of the first three principal components of the normalized gene expression profiles of all 17,777 genes passing quality control shows clear separation of 12 and 24 hr hypoxia-exposed samples versus control and from reoxygenated samples. Bar charts: mean ± s.e.m.
C Chambers, supplied by BioSpherix, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-chamber/bio_rxiv__64898__2026__02__09__704975-225-8-9?v=BioSpherix
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c chambers - by Bioz Stars, 2026-08
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( A ) Oxygen levels (PO 2 (mmHg)) in cell culture media under control conditions and following exposure to hypoxia for 24 hr in the C-chamber hypoxia sub-chamber (Biospherix; unpaired t -test, p<0.0001); ( B ) Hierarchical clustering, using Ward’s criterion, of the first three principal components of the normalized gene expression profiles of all 17,777 genes passing quality control shows clear separation of 12 and 24 hr hypoxia-exposed samples versus control and from reoxygenated samples. Bar charts: mean ± s.e.m.

Journal: eLife

Article Title: Adrenomedullin restores the human cortical interneurons migration defects induced by hypoxia

doi: 10.7554/eLife.108134

Figure Lengend Snippet: ( A ) Oxygen levels (PO 2 (mmHg)) in cell culture media under control conditions and following exposure to hypoxia for 24 hr in the C-chamber hypoxia sub-chamber (Biospherix; unpaired t -test, p<0.0001); ( B ) Hierarchical clustering, using Ward’s criterion, of the first three principal components of the normalized gene expression profiles of all 17,777 genes passing quality control shows clear separation of 12 and 24 hr hypoxia-exposed samples versus control and from reoxygenated samples. Bar charts: mean ± s.e.m.

Article Snippet: For these experiments, we induced hypoxia using the C-chamber hypoxia sub-chamber (Biospherix).

Techniques: Cell Culture, Control, Gene Expression